npm · PyPI94Exceptionalhealth index
TypeScript★ 923↓ 36.1K/moOct 22, 2026
PyPI92Excellenthealth index

runloopai/api-client-pythonOfficial Python SDK for Runloop — secure Linux sandboxes (Devboxes) where AI agents run code, edit files, and expose ports
Python★ 28↓ 502K/moSep 14, 2026
crates.io91Excellenthealth index
Rust★ 10.3K↓ 2,155/moSep 18, 2026
npm86Excellenthealth index
TypeScript★ 3,708↓ 6,475/moSep 13, 2026
npm · crates.io84Excellenthealth index

Cloudgeni-ai/opengeniOpen, self-hostable agentic runtime for organizations — durable, replayable agent sessions, human approvals, governed credentials and memory, running in managed sandboxes or on your own hardware. Apache-2.0.
TypeScript★ 128↓ 44K/moSep 12, 2026
Go · npm84Excellenthealth index

FootprintAI/ContainariumOpen-source agent runtime — SSH-native isolation, eBPF egress policy, Kubernetes + LXC backends, GPU passthrough, MCP-native CLI
Go★ 277Sep 10, 2026
npm84Excellenthealth index

griffinwork40/agent-afkThe coding agent you don’t have to watch. Start a task and walk away. AFK builds the feature, verifies its own work, and texts you when it’s done. You come back to a receipt of every step, every decision, and what’s waiting on you. If it’s unsure, it stops and asks instead of guessing.
TypeScript★ 61↓ 178.8K/moOct 20, 2026
npm · crates.io84Excellenthealth index

olo-dot-io/Uni-CLIOne command for every interface—search, run, and inspect real software across APIs, browsers, desktops, local tools, and MCP.
TypeScript★ 271↓ 1,845/moSep 10, 2026
npm84Excellenthealth index
TypeScript★ 0↓ 393/moSep 7, 2026
PyPI84Excellenthealth index

runtm-ai/runtmOpen-source sandboxes where coding agents build and deploy. Spin up isolated environments where Claude Code, Cursor, and other agents code and deploy software.
Python · Go★ 297↓ 1,793/moSep 14, 2026
Go83Excellenthealth index
Go★ 70Sep 12, 2026
npm83Excellenthealth index
TypeScript★ 7↓ 86/moSep 20, 2026
npm · crates.io83Excellenthealth index

runxhq/runxthe governed runtime for agent skill workflows, off the leash but on the record
Rust · TypeScript★ 84↓ 1,833/moSep 8, 2026
npm83Excellenthealth index

usetheokit/theokit-sdkOpen-source TypeScript SDK and agent runtime you own end to end. Agent.create / prompt / stream / resume, 43 LLM providers on your own keys, MCP with OAuth PKCE, subagents, workflows, evals, memory, and a bubblewrap+seccomp kernel sandbox for tool execution. Local-first, opt-in cloud, Apache-2.0.
TypeScript★ 3↓ 14.1K/moOct 13, 2026
Go81Excellenthealth index

RenseiAI/donmaiDonmai is an open-source workflow runtime that runs, retries, and audits multi-step agent tasks on your machine. The same binary powers Rensei in production. MIT-licensed.
Go★ 5Sep 9, 2026
PyPI80Excellenthealth index
Python · TypeScript★ 18↓ 31.1K/moSep 9, 2026
Go · npm80Excellenthealth index

devlikebear/tarsLocal AI agent runtime in a single Go binary — browser console, sub-agents, memory, scheduled jobs.
Go · TypeScript · Svelte★ 2Oct 4, 2026

Keesan12/martin-loopMake AI coding agents safe to scale autonomously: assign work, cap spend, enforce policy, verify output, roll back failures, learn from loops, and prove ROI across every repo.
TypeScript · JavaScript★ 51↓ 2,344/moSep 11, 2026

comisai/comisOpen-source security-first runtime for AI agents that learn and act across sessions.
TypeScript★ 5↓ 962/moSep 11, 2026
PyPI · npm75Goodhealth index

Masterplanner25/aindy-runtimeSelf-hosted runtime for AI agents and workflows. Durable execution, capability-gated tools, human approval gates, and a memory system that accumulates. Runs survive restarts and resume where they stopped. Mount your domain logic as a plugin package or drive it over the HTTP SDK
Python★ 1↓ 4,113/moSep 16, 2026
TypeScript★ 2↓ 13.8K/moOct 20, 2026
npm · crates.io75Goodhealth index

brianonbased-dev/HoloScriptA general-purpose semantic systems programming language. Describe a system once; real compilers lower the same source into engine builds, backend services, robots, web runtimes, and headset apps. Not a scripting language.
TypeScript★ 7↓ 1,544/moSep 8, 2026
crates.io · npm75Goodhealth index

holon-run/holonA local workbench for agents doing continuous work across sessions, commands, human input, and external events.
Rust · TypeScript★ 140↓ 25/moSep 20, 2026

o-stepper/graphorinProject Graphorin is a TypeScript framework for personal AI assistants and long-living agents with rich memory, durable workflow, and observability out of the box.
TypeScript★ 3↓ 2,359/moSep 15, 2026
Go · npm71Goodhealth index
Go · TypeScript★ 1,339Sep 11, 2026
PyPI · npm71Goodhealth index

hoonseokyoon/monoid-agent-kernelEmbeddable agent kernel for durable, provider-neutral LLM agents with permissions, pluggable tools, observability, and subagents.
Python★ 1↓ 2,286/moSep 15, 2026

Agentplat/agentplatOpen-source TypeScript framework for persistent human-agent collaboration, with shared artifacts, human approvals and controlled execution on your infrastructure.
TypeScript · JavaScript★ 1↓ 4,155/moSep 12, 2026
npm · PyPI69Goodhealth index

remoteclaw/remoteclawUniversal AI agent middleware. Gives CLI agents (Claude Code, Gemini CLI, Codex, OpenCode) 22+ messaging channels, persistent sessions, and 50 MCP tools. Fork of OpenClaw with the platform layer replaced by AgentRuntime.
TypeScript · Swift★ 30↓ 6,360/moSep 18, 2026

GizClaw/flowcraftProduction-grade Go SDK for building AI agents with long-term memory, knowledge retrieval, and voice — runnable as a library, a daemon, or a real-time pipeline.
Go★ 416Sep 11, 2026

KPO-Tech/seshatOpen-source Go agent runtime for autonomous AI systems and multi-agent automation. MCP, RAG, 15+ LLM providers and 60+ built-in tools in a single binary.
Go★ 4Sep 11, 2026