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deepset-ai/haystackOpen-source AI orchestration framework for building context-engineered, production-ready LLM applications. Design modular pipelines and agent workflows with explicit control over retrieval, routing, memory, and generation. Built for scalable agents, RAG, multimodal applications, semantic search, and conversational systems.
Python★ 26.5KSep 16, 2026
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onnx/onnxOpen standard for machine learning interoperability
Python · C++★ 21.5K↓ 13.5M/moSep 16, 2026
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pingcap/tidbTiDB is built for agentic workloads that grow unpredictably, with ACID guarantees and native support for transactions, analytics, and vector search. No data silos. No noisy neighbors. No infrastructure ceiling.
Go★ 40.5KSep 16, 2026
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stacklok/toolhiveToolHive is an enterprise-grade platform for running and managing Model Context Protocol (MCP) servers.
Go★ 2,165Sep 14, 2026
PyPI · Go · crates.io100Exceptionalhealth index

wandb/wandbThe AI developer platform. Use Weights & Biases to train and fine-tune models, and manage models from experimentation to production.
Python · Go★ 11.2K↓ 26.6M/moAug 27, 2026
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TypeScript · JavaScript★ 1,914↓ 1.3M/moSep 10, 2026
PyPI · crates.io · npm99Exceptionalhealth index

IBM/mcp-context-forgeAn AI Gateway, registry, and proxy that sits in front of any MCP, A2A, or REST/gRPC APIs, exposing a unified endpoint with centralized discovery, guardrails and management. Optimizes Agent & Tool calling, and supports plugins.
Python★ 4,477Sep 16, 2026
npm · Packagist99Exceptionalhealth index

WordPress/gutenbergThe Block Editor project for WordPress and beyond. Plugin is available from the official repository.
JavaScript · TypeScript · PHP★ 11.8K↓ 3.8M/moAug 27, 2026
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ag2ai/ag2AG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3x
Python · MDX★ 4,891↓ 494.4K/moAug 28, 2026
PyPI · crates.io · npm99Exceptionalhealth index

awslabs/cli-agent-orchestratorMulti-agent orchestration for AI coding CLIs — Claude Code, Kiro, Codex, and more, coordinated in isolated tmux sessions
Python★ 1,455↓ 1,125/moOct 20, 2026
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crewAIInc/crewAIFramework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.
Python★ 58.7K↓ 27.6M/moSep 16, 2026
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github/spec-kit💫 Toolkit to help you get started with Spec-Driven Development
Python★ 137.2KSep 16, 2026
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google/adk-pythonAn open-source, code-first Python toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.
Python★ 21.6K↓ 18.7M/moSep 16, 2026
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microsoft/agent-frameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.
Python · C#★ 13.2K↓ 1.5M/moAug 27, 2026
NuGet · PyPI99Exceptionalhealth index
C++ · Python★ 1,119Sep 11, 2026
PyPI99Exceptionalhealth index
C# · Python★ 28.6KSep 16, 2026
PyPI · npm99Exceptionalhealth index

mlflow/mlflowThe open source AI engineering platform for agents, LLMs, and ML models. MLflow enables teams of all sizes to debug, evaluate, monitor, and optimize production-quality AI applications while controlling costs and managing access to models and data.
Python · TypeScript★ 28K↓ 28.6M/moSep 16, 2026
npm99Exceptionalhealth index

mui/mui-xMUI X: Build complex and data-rich applications using a growing list of advanced React components, like the Data Grid, Date and Time Pickers, Charts, and more!
TypeScript★ 5,838↓ 41.2M/moAug 27, 2026
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Python★ 4,442↓ 14.6M/moAug 27, 2026
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ultralytics/ultralyticsUltralytics YOLO27, YOLO26, YOLO11, YOLOv8 — object detection, instance segmentation, semantic segmentation, image classification, pose estimation, object tracking
Python★ 61.7KSep 16, 2026
npm · Maven · Packagist +198Exceptionalhealth index
TypeScript · JavaScript★ 12.6K↓ 21.4K/moOct 14, 2026
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CherryHQ/cherry-studioAI productivity studio with smart chat, autonomous agents, and 300+ assistants. Unified access to frontier LLMs
TypeScript★ 52.4K↓ 4,930/moOct 4, 2026
PyPI · npm98Exceptionalhealth index

ComposioHQ/composioComposio powers 1000+ toolkits, tool search, context management, authentication, and a sandboxed workbench to help you build AI agents that turn intent into action.
TypeScript · Python★ 30.2K↓ 1.7M/moSep 16, 2026
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InsForge/InsForgeThe all-in-one, open-source backend platform for agentic coding. InsForge gives your coding agent database, auth, storage, compute, hosting, and AI gateway to ship full-stack apps end-to-end.
TypeScript★ 13KSep 16, 2026
PyPI · npm98Exceptionalhealth index

ModelEngine-Group/nexentNexent is a zero-code platform for auto-generating production-grade AI agents using Harness Engineering principles — unified tools, skills, memory, and orchestration with built-in constraints, feedback loops, and control planes.
Python · TypeScript★ 5,839Aug 28, 2026
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NVIDIA/NeMo-Agent-ToolkitThe NVIDIA NeMo Agent toolkit is an open-source library for efficiently connecting and optimizing teams of AI agents.
Python★ 2,630↓ 144.1K/moSep 11, 2026
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Python★ 10.3K↓ 1M/moSep 17, 2026
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TypeScript★ 604↓ 116M/moSep 10, 2026
PyPI · npm98Exceptionalhealth index
Python · TypeScript★ 23.2KOct 19, 2026
PyPI · crates.io98Exceptionalhealth index
Python · Rust★ 1,195↓ 966.4K/moAug 27, 2026