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deepset-ai/haystackOpen-source AI orchestration framework for building context-engineered, production-ready LLM applications. Design modular pipelines and agent workflows with explicit control over retrieval, routing, memory, and generation. Built for scalable agents, RAG, multimodal applications, semantic search, and conversational systems.
Python★ 26.5KSep 16, 2026
PyPI · crates.io · npm99Exceptionalhealth index

IBM/mcp-context-forgeAn AI Gateway, registry, and proxy that sits in front of any MCP, A2A, or REST/gRPC APIs, exposing a unified endpoint with centralized discovery, guardrails and management. Optimizes Agent & Tool calling, and supports plugins.
Python★ 4,477Sep 16, 2026
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ag2ai/ag2AG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3x
Python · MDX★ 4,891↓ 494.4K/moAug 28, 2026
PyPI · crates.io · npm99Exceptionalhealth index

awslabs/cli-agent-orchestratorMulti-agent orchestration for AI coding CLIs — Claude Code, Kiro, Codex, and more, coordinated in isolated tmux sessions
Python★ 1,455↓ 1,125/moOct 20, 2026
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google/adk-pythonAn open-source, code-first Python toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.
Python★ 21.6K↓ 18.7M/moSep 16, 2026
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microsoft/agent-frameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.
Python · C#★ 13.2K↓ 1.5M/moAug 27, 2026
PyPI · npm98Exceptionalhealth index

ModelEngine-Group/nexentNexent is a zero-code platform for auto-generating production-grade AI agents using Harness Engineering principles — unified tools, skills, memory, and orchestration with built-in constraints, feedback loops, and control planes.
Python · TypeScript★ 5,839Aug 28, 2026
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bytedance/deer-flowAn open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
Python · TypeScript★ 82.5KSep 16, 2026
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Java · TypeScript★ 10.7KAug 28, 2026
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mesa/mesaMesa is an open-source Python library for agent-based modeling, ideal for simulating complex systems and exploring emergent behaviors.
Python★ 3,839↓ 53.6K/moSep 13, 2026
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Python★ 33.6K↓ 196.5K/moOct 20, 2026
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google/adk-jsAn open-source, code-first Typescript toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.
TypeScript★ 1,398↓ 693.4K/moSep 14, 2026
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AgileRL/AgileRLStreamlining reinforcement learning with RLOps. State-of-the-art RL algorithms and tools, with 10x faster training through evolutionary hyperparameter optimization.
Python★ 951Sep 11, 2026
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Python★ 33.6K↓ 31.3K/moSep 16, 2026
npm · crates.io94Exceptionalhealth index

Hmbown/CodewhaleOpen-source coding agent for your terminal, built in Rust and on a journey of continuous community improvement. Issues and PRs welcome.
Rust★ 41K↓ 26.2K/moSep 16, 2026
npm · Go94Exceptionalhealth index

Untrivial-ai/agent-orchestratorAgent IDE that enables you to manage fleets of coding agents. It comes with an agentic orchestrator that plans tasks, spawns agents, and autonomously handles CI fixes, merge conflicts, and code reviews.
Go · TypeScript★ 10.1KAug 28, 2026
PyPI · npm94Exceptionalhealth index

doobidoo/mcp-memory-serviceOpen-source persistent memory for AI agent pipelines (LangGraph, CrewAI, AutoGen) and Claude. REST API + knowledge graph + autonomous consolidation.
Python · HTML · JavaScript★ 2,016↓ 8,649/moOct 15, 2026
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monocle2ai/monocleMonocle is a framework for tracing GenAI app code. This repo contains implementation of Monocle for GenAI apps written in Python.
Python★ 337↓ 50.8K/moAug 28, 2026
PyPI · npm94Exceptionalhealth index

omnigent-ai/omnigentOmnigent is an open-source AI agent framework and meta-harness: orchestrate Claude Code, Codex, Cursor, Pi, and custom agents — swap harnesses without rewriting, enforce policies and sandboxing, and collaborate in real time from any device.
Python · TypeScript★ 10KSep 16, 2026
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vstorm-co/pydantic-deepagentsOpen-source, self-hosted Claude Code - a terminal AI assistant and the Python framework behind it. Tool-calling, sandboxed execution, multi-agent teams, skills, checkpoints, unlimited context - on Pydantic AI, any model.
Python★ 1,062↓ 141.9K/moSep 15, 2026
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Lumiwealth/lumibotBacktestable AI trading agents and Python algorithmic trading strategies for stocks, options, crypto, futures, forex, SEC filings, FRED macro data, and real brokers.
Python★ 2,051↓ 152.5K/moSep 10, 2026
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TypeScript · JavaScript★ 39.2K↓ 21K/moSep 16, 2026
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Python★ 152↓ 6,660/moSep 8, 2026
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sipyourdrink-ltd/bernsteinThe open‑source AI Agents Governance & Orchestration framework: write the rules declaratively, Bernstein enforces them and produces the verifiable, replayable record. Free, Apache-2.0. https://bernstein.run
Python★ 1,178Sep 14, 2026
Go93Exceptionalhealth index

trpc-group/trpc-agent-goA Go framework for building production agent systems with graph workflows, tools, memory, A2A, AG-UI, MCP, evaluation, and observability.
Go★ 1,781Sep 11, 2026
npm · PyPI · crates.io91Excellenthealth index

MemoriLabs/MemoriMemori is agent-native memory infrastructure. A LLM-agnostic layer that turns agent execution and conversation into structured, persistent state for production systems. Built for enterprise, Memori works with the data infrastructure you already run, no rip-and-replace, and deploys across managed cloud, single-tenant cloud, VPC, and on-premises.
Python · TypeScript · Rust★ 16.8K↓ 250/moSep 17, 2026
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ZaxbyHub/opencode-swarm Architect-centric agentic swarm plugin for OpenCode. Hub-and-spoke orchestration with SME consultation, code generation, and QA review.
TypeScript★ 509↓ 19.5K/moOct 20, 2026
npm · NuGet91Excellenthealth index
TypeScript★ 3,175↓ 15.9K/moSep 15, 2026
Maven91Excellenthealth index

google/adk-javaAn open-source, code-first Java toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.
Java★ 1,720Sep 14, 2026
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xerrors/Yuxi可私有部署的多租户知识智能体平台:统一 RAG、知识图谱、多智能体、MCP/Skills、沙盒与权限管理。Self-hosted knowledge agent platform for RAG, knowledge graphs and multi-agent workflows.
Python · Vue★ 6,572↓ 47/moAug 28, 2026