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microsoft/agent-frameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.
Python · C#★ 13.2K↓ 1.5M/moAug 27, 2026
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Python★ 3,475↓ 424.3K/moJul 30, 2026
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pandas-dev/pandasFlexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, statistical functions, and much more
Python★ 49.5K↓ 770M/moAug 11, 2026
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prowler-cloud/prowlerProwler is the world’s most widely used open-source cloud security platform that automates security and compliance across any cloud environment.
Python · TypeScript★ 14.7K↓ 217.7K/moAug 27, 2026
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Python★ 4,442↓ 14.6M/moAug 27, 2026
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Python★ 19.1K↓ 180M/moAug 4, 2026
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Python★ 4,190↓ 17.4M/moAug 28, 2026
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pypa/cibuildwheel🎡 Build Python wheels for all the platforms with minimal configuration.
Python★ 2,248Jul 18, 2026
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pyvista/pyvista3D visualization and mesh analysis for science and engineering
Python★ 3,749↓ 1.2M/moJul 21, 2026
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quantumlib/CirqPython framework for creating, editing, and running Noisy Intermediate-Scale Quantum (NISQ) circuits.
Python★ 5,054↓ 796.3K/moAug 28, 2026
npm · PyPI · Hex +299Exceptionalhealth index

taskforcesh/bullmqBullMQ - Message Queue and Batch processing for NodeJS, Python, .NET, Elixir, Rust and PHP based on Redis or PostgreSQL
TypeScript · Rust · Elixir★ 9,336↓ 36.1M/moAug 27, 2026
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wagtail/wagtailA Django content management system focused on flexibility and user experience
Python · JavaScript★ 20.4KAug 12, 2026
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ComposioHQ/composioComposio powers 1000+ toolkits, tool search, context management, authentication, and a sandboxed workbench to help you build AI agents that turn intent into action.
TypeScript · Python★ 29.5KAug 5, 2026
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Eventual-Inc/DaftHigh-performance data engine for AI and multimodal workloads. Process images, audio, video, and structured data at any scale
Rust · Python · Jupyter Notebook★ 5,731↓ 6.3M/moAug 28, 2026
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NVIDIA-NeMo/GuardrailsNeMo Guardrails is an open-source toolkit for easily adding programmable guardrails to LLM-based conversational systems.
Python★ 6,930↓ 394.8K/moAug 12, 2026
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NVIDIA/warpA Python framework for GPU-accelerated simulation, robotics, and machine learning.
Python · C++★ 7,037↓ 1.2M/moAug 28, 2026
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Python★ 10.2K↓ 1M/moAug 12, 2026
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Python★ 4,889↓ 1.9M/moAug 27, 2026
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PennyLaneAI/pennylanePennyLane is an open-source quantum software platform for quantum computing, quantum machine learning, and quantum chemistry. Create meaningful quantum algorithms, from inspiration to implementation.
Python★ 3,404Aug 13, 2026
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Python★ 1,148↓ 1.5M/moAug 8, 2026
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SQLMesh/sqlmeshScalable and efficient data transformation framework - backwards compatible with dbt.
Python · TypeScript★ 3,263Sep 1, 2026
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Significant-Gravitas/AutoGPTAutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.
Python · TypeScript★ 185.8KAug 4, 2026
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ansible/moleculeAn ansible-native testing framework for collections, playbooks, and roles with configurable workflows for testing any system or service
Python★ 4,128Aug 8, 2026
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Python · GLSL · TypeScript★ 365Jul 17, 2026
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Python★ 75↓ 42.2K/moJul 30, 2026
PyPI · crates.io · Maven +198Exceptionalhealth index

apache/foryA blazingly fast multi-language serialization framework for idiomatic domain objects, schema IDL, and cross-language data exchange.
Java · Python★ 4,519↓ 4,472/moAug 28, 2026
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apache/sedonaA cluster computing framework for processing large-scale geospatial data
Java · Scala · Python★ 2,378↓ 2.2M/moAug 13, 2026
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apify/crawlee-pythonCrawlee—A web scraping and browser automation library for Python to build reliable crawlers. Extract data for AI, LLMs, RAG, or GPTs. Download HTML, PDF, JPG, PNG, and other files from websites. Works with Parsel, BeautifulSoup, Playwright, and raw HTTP. Both headful and headless mode. With proxy rotation.
Python · MDX★ 9,426Aug 12, 2026
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Python · Jinja★ 405↓ 25.5K/moJul 29, 2026
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astral-sh/uvAn extremely fast Python package and project manager, written in Rust.
Rust★ 88.3KAug 4, 2026