PyPI100Exceptionalhealth index
Python · C★ 5,288↓ 3.4M/moAug 28, 2026
PyPI · RubyGems98Exceptionalhealth index

materialsproject/pymatgenPython Materials Genomics (pymatgen) is a robust materials analysis code that defines classes for structures and molecules with support for many electronic structure codes. It powers the Materials Project.
Python · Polar★ 1,963↓ 763.4K/moSep 10, 2026
PyPI · npm97Exceptionalhealth index

Opentrons/opentronsSoftware for writing protocols and running them on the Opentrons Flex and Opentrons OT-2
Python · TypeScript★ 525↓ 12.8K/moOct 19, 2026
PyPI97Exceptionalhealth index
Python★ 9,112↓ 5.5M/moAug 28, 2026
NuGet96Exceptionalhealth index
C#★ 3,697Sep 12, 2026
Go96Exceptionalhealth index
Go★ 1,965Sep 16, 2026
Maven96Exceptionalhealth index
Java★ 1,038Sep 13, 2026
NuGet96Exceptionalhealth index
C#★ 9,358Sep 15, 2026
crates.io96Exceptionalhealth index

typst/typstA markup-based typesetting system that is powerful and easy to learn.
Rust · Typst★ 56K↓ 1.5M/moSep 16, 2026
npm · PyPI95Exceptionalhealth index
Python · TypeScript · Vue★ 1,872↓ 245/moOct 18, 2026
crates.io95Exceptionalhealth index

tracel-ai/burnBurn is a next generation tensor library and Deep Learning Framework that doesn't compromise on flexibility, efficiency and portability.
Rust★ 15.9K↓ 747.6K/moSep 16, 2026
crates.io94Exceptionalhealth index

dusk-network/plonkPure Rust implementation of the PLONK ZKProof System done by the Dusk team
Rust★ 643↓ 7,867/moOct 10, 2026
crates.io · npm · PyPI94Exceptionalhealth index
Rust · Python★ 670↓ 7,631/moSep 4, 2026
npm · PyPI94Exceptionalhealth index
TypeScript★ 1,220↓ 20.2K/moSep 17, 2026
PyPI94Exceptionalhealth index
HTML · Lobster · Python★ 27↓ 708.2K/moSep 9, 2026
crates.io · npm · PyPI94Exceptionalhealth index

pykeio/ortFast ML inference & training for ONNX models in Rust
Rust★ 2,477↓ 4.3M/moAug 27, 2026
PyPI93Exceptionalhealth index
Python★ 1,645↓ 209.8K/moSep 12, 2026
crates.io93Exceptionalhealth index

sonos/tractTiny, no-nonsense, self-contained, Tensorflow and ONNX inference
Rust★ 3,061↓ 1,860/moSep 9, 2026
crates.io92Excellenthealth index
Rust★ 1,389↓ 3.3M/moOct 18, 2026
crates.io92Excellenthealth index
Rust★ 135↓ 156.7K/moOct 20, 2026
C++★ 1,132Oct 20, 2026
PyPI · npm92Excellenthealth index
Python★ 322↓ 2,474/moOct 16, 2026
npm · crates.io92Excellenthealth index

ruvnet/RuVectorRuVector provides High Performance, Real-Time decisions and agent memory , Self-Learning Ai, Vector GNN DB built in Rust.
Rust · TypeScript★ 4,599↓ 489.6K/moOct 20, 2026
crates.io92Excellenthealth index

tracel-ai/cubeclMulti-platform high-performance compute language extension for Rust.
Rust★ 2,372↓ 942.9K/moSep 14, 2026
npm91Excellenthealth index
TypeScript · HTML★ 36↓ 11.4K/moSep 14, 2026
PyPI91Excellenthealth index

glotzerlab/freudPowerful, efficient particle trajectory analysis in scientific Python.
C++ · Python★ 329↓ 4,771/moSep 13, 2026
PyPI91Excellenthealth index

hgrecco/pintOperate and manipulate physical quantities in Python
Python★ 2,795↓ 5.7M/moSep 12, 2026
npm · crates.io91Excellenthealth index
Rust · C++ · TypeScript★ 11.3K↓ 73.9K/moOct 20, 2026
crates.io91Excellenthealth index

smartcorelib/smartcoreA comprehensive library for machine learning and numerical computing. Apply Machine Learning with Rust leveraging first principles.
Rust★ 967↓ 48.6K/moOct 20, 2026
PyPI90Excellenthealth index

LSSTDESC/CCLDESC Core Cosmology Library: cosmology routines with validated numerical accuracy
C · Python★ 160↓ 5,060/moSep 13, 2026