Python★ 190↓ 92.3M/moSep 16, 2026
Go · Maven · PyPI73Goodhealth index

Liam0205/pineappleMulti-runtime DAG pipeline engine — declare in Python, execute in Go / Java / Python, decouple with JSON.
Go · C++ · Java★ 13Sep 9, 2026

MaxFreedomPollard/CompartmentEncrypted, fully offline agentic memory. One click install, GUI w/ memory map, all OS and agents. Superior memory creation, storage and retrieval.
Python★ 587↓ 1,943/moSep 14, 2026
PyPI · npm73Goodhealth index
Python★ 2↓ 2,160/moOct 19, 2026
Python · HTML★ 385Oct 16, 2026

PDBeurope/ccdutilsA set of python tools to deal with PDB chemical components definitions for small molecules, taken from the wwPDB Chemical Component Dictionary, uses RDKit
Python★ 85↓ 265.2K/moOct 22, 2026
Python★ 275↓ 3,725/moSep 19, 2026

Perception-Dynamics-Inc/a11y-computer-usea11y-computer-use: accessibility-first computer use for AI agents. Pruned a11y-tree snapshots, element refs instead of pixel coordinates, a safety layer, an MCP server and CLI. macOS, Windows, Linux, and Chromium over CDP.
Python★ 0↓ 3,747/moOct 8, 2026
Python★ 45↓ 41.9K/moSep 13, 2026

RECHE23/real-regexLinear-time, ReDoS-safe C++20 header-only regex engine with bounded lookarounds + an re-compatible Python binding
C++ · Python★ 5↓ 8,979/moOct 20, 2026
PyPI · npm73Goodhealth index

Soju06/rvwLayered, replicated, self-adjudicating code review orchestrator
Python · TypeScript★ 5↓ 3,421/moSep 18, 2026
Python★ 43↓ 221/moSep 20, 2026
Python★ 154Sep 12, 2026

aerkalov/ebooklibA versatile Python library for EPUB2/EPUB3 manipulation and processing.
Python★ 1,808↓ 1M/moSep 12, 2026
Python★ 0↓ 3,165/moOct 15, 2026

ajinabraham/njsscannjsscan is a semantic aware SAST tool that can find insecure code patterns in your Node.js applications.
JavaScript · Python★ 454↓ 99.4K/moSep 21, 2026
Python★ 1,204↓ 17.9M/moAug 27, 2026

alkaline-ml/pmdarimaA statistical library designed to fill the void in Python's time series analysis capabilities, including the equivalent of R's auto.arima function.
Python★ 1,736↓ 1.8M/moSep 19, 2026

apowerb/apowerbThe open-source agentic framework to build, orchestrate, and operate production AI agents.
Python★ 41↓ 5,285/moSep 29, 2026

araffin/sbxSBX: Stable Baselines Jax (SB3 + Jax) RL algorithms
Python★ 613↓ 929/moOct 22, 2026

arcsecond-io/cliThe Command Line Interface (CLI) & Python Module for Arcsecond.io.
Python★ 10↓ 2,065/moOct 21, 2026
PyPI · Go73Goodhealth index

artefactual-labs/pygfriedpygfried is a CPython extension that brings Siegfried, the Go-based signature file format identification tool, to Python.
Go · Python · C★ 7↓ 552/moSep 13, 2026
Python★ 1↓ 5,609/moSep 16, 2026
Python★ 3↓ 2,441/moOct 20, 2026
Python★ 250↓ 18K/moOct 16, 2026
Python★ 3↓ 205.2K/moOct 20, 2026
Python★ 6↓ 2,016/moOct 18, 2026
Go · crates.io · npm73Goodhealth index

c3-oss/codexcwrun codex, claude code or grok build non-interactively from code
Rust · C# · Go★ 1Sep 11, 2026

caiovicentino/polymarket-mcp-server🤖 AI-Powered MCP Server for Polymarket - Enable Claude to trade prediction markets with 45 tools, real-time monitoring, and enterprise-grade safety features
Python★ 690Sep 30, 2026
Python★ 128Sep 9, 2026