#python

a UNIX shell toolkit for processing and analyzing multiple sequence alignments and phylogenies

Retrieve information from typeshed and other typing stubs

Converts text to speech in realtime

Evidence-backed proof of done for Claude Code, Codex, Cursor, and other AI coding agents. Run real checks, bind results to current Git state, and know what is ready for human review.

Deep learning framework for proteomics

Self-hosted runtime for AI agents and workflows. Durable execution, capability-gated tools, human approval gates, and a memory system that accumulates. Runs survive restarts and resume where they stopped. Mount your domain logic as a plugin package or drive it over the HTTP SDK

High-performance SASA (Solvent Accessible Surface Area) calculation in Zig with Python bindings

Python bindings to SUNDIALS differential algebraic equation solvers

NeLux: High-performance video processing for Python, powered by FFmpeg and PyTorch. Ultra-fast video decoding directly to tensors.

Windows Agent Arena and GUI-agent evaluation for OpenAdapt. Live support surface. Install the product with pip install openadapt; this repo is the eval harness, including WAA.

AI-powered OSINT agent with interactive REPL, MCP server, and CLI. 20 tools. Works with Claude, GPT-4, or local models. For authorized security research only.

Overlapping-generations macroeconomic model for evaluating fiscal policy in the United States

The best PTT library

Python SDK for the VGI (Vector Gateway Interface) protocol — host DuckDB scalar, table, aggregate, and table-in-out functions in an external worker over Arrow IPC.

A Python validator for SHACL

Graph-based tool retrieval for LLM agents — 248 tools → 82% accuracy, 79% fewer tokens. Zero dependencies. OpenAPI / MCP / LangChain.

Python API client for SPAN Panel - provides async interface to control circuits, monitor power usage, and manage panel settings

Terminal toolkit for large Calibre libraries: catalogs, stats, deep audits (tree, FTS coverage, ISBNs, covers, duplicates), Calibre-parity search with --restrict scoping, opt-in write verbs and set mode, and a three-phase acquisition run (screen, sign, import). Frontend over the cquarry library; no calibredb needed.

Complete lxml external type annotation

adcc: Seamlessly connect your program to ADC

A python workflows library that supports writing Processes with a well defined set of inputs and outputs that can be strung together.

Workflow engine where ops can yield — same async DAG handles batch jobs and event-driven streaming pipelines (pipecat-style callbot, STT → LLM → TTS). Python frontend, drop-in Rust runtime; 2–3× faster on chains, 10–30× on production workloads. LLMs, agents, RAG, native compute as first-class ops.

Sampling profiler for Python programs

The most popular ClickHouse plugin for Airflow. 🔝 Top-1% downloads on PyPI: https://pypi.org/project/airflow-clickhouse-plugin! Based on mymarilyn/clickhouse-driver.

Python bindings for oxidize-pdf — generate, parse, split, merge & manipulate PDFs with native Rust performance. No C deps, no Java, no subprocesses.

A SQLite extension that adds graph database capabilities with Cypher query language support and built-in graph algorithms.

Python library and CLI for validating and formatting Chilean RUT identifiers.

pytest for AI agents - Autonomous red-teaming, behavioral monitoring & security testing for LLM agents

A self-hosted habit tracking app without "Goals"

Blender addon for the DCC Model Context Protocol (MCP) ecosystem — embeds a Streamable HTTP MCP server directly inside Blender