
FelixTheC/strongtypingDecorator which checks whether the function is called with the correct type of parameters.
Python★ 121Sep 19, 2026
Python★ 212Sep 10, 2026
PyPI · Go75Goodhealth index
Python · Go★ 0↓ 974/moSep 19, 2026

JLSteenwyk/PhyKITa UNIX shell toolkit for processing and analyzing multiple sequence alignments and phylogenies
Python★ 91↓ 7,664/moSep 12, 2026
Python★ 31↓ 2M/moAug 27, 2026
Python★ 4,016↓ 6,776/moAug 28, 2026

Lians-ai/LiansEvidence-backed proof of done for Claude Code, Codex, Cursor, and other AI coding agents. Run real checks, bind results to current Git state, and know what is ready for human review.
Python★ 11Sep 14, 2026
Jupyter Notebook★ 158Sep 19, 2026
PyPI · npm75Goodhealth index

Masterplanner25/aindy-runtimeSelf-hosted runtime for AI agents and workflows. Durable execution, capability-gated tools, human approval gates, and a memory system that accumulates. Runs survive restarts and resume where they stopped. Mount your domain logic as a plugin package or drive it over the HTTP SDK
Python★ 1↓ 4,113/moSep 16, 2026
PyPI · npm75Goodhealth index

N283T/zsasaHigh-performance SASA (Solvent Accessible Surface Area) calculation in Zig with Python bindings
Zig · Python★ 10↓ 1,820/moSep 14, 2026
Python · Cython★ 27↓ 6,206/moOct 15, 2026

NevermindNilas/NeluxNeLux: High-performance video processing for Python, powered by FFmpeg and PyTorch. Ultra-fast video decoding directly to tensors.
C++ · Python★ 29↓ 3,141/moSep 11, 2026

OpenAdaptAI/openadapt-evalsWindows Agent Arena and GUI-agent evaluation for OpenAdapt. Live support surface. Install the product with pip install openadapt; this repo is the eval harness, including WAA.
Python★ 4↓ 3,043/moSep 14, 2026

OpenOSINT/OpenOSINTAI-powered OSINT agent with interactive REPL, MCP server, and CLI. 20 tools. Works with Claude, GPT-4, or local models. For authorized security research only.
Python · JavaScript★ 1,599↓ 2,892/moSep 18, 2026

PSLmodels/OG-USAOverlapping-generations macroeconomic model for evaluating fiscal policy in the United States
Python★ 29↓ 151/moSep 19, 2026
Python★ 732↓ 2,718/moSep 11, 2026

Query-farm/vgi-pythonPython SDK for the VGI (Vector Gateway Interface) protocol — host DuckDB scalar, table, aggregate, and table-in-out functions in an external worker over Arrow IPC.
Python★ 4↓ 3,130/moSep 13, 2026
Python★ 349↓ 1.2M/moSep 17, 2026
PyPI · npm75Goodhealth index

SonAIengine/graph-tool-callGraph-based tool retrieval for LLM agents — 248 tools → 82% accuracy, 79% fewer tokens. Zero dependencies. OpenAPI / MCP / LangChain.
Python★ 17↓ 2,636/moSep 15, 2026

SpanPanel/span-panel-apiPython API client for SPAN Panel - provides async interface to control circuits, monitor power usage, and manage panel settings
Python★ 3↓ 2,098/moOct 19, 2026

VirInvictus/CalibreQuarryTerminal toolkit for large Calibre libraries: catalogs, stats, deep audits (tree, FTS coverage, ISBNs, covers, duplicates), Calibre-parity search with --restrict scoping, opt-in write verbs and set mode, and a three-phase acquisition run (screen, sign, import). Frontend over the cquarry library; no calibredb needed.
Python★ 2↓ 3,472/moOct 11, 2026
Python★ 84↓ 2.1M/moSep 16, 2026
Python · C++★ 42↓ 384/moSep 11, 2026

aiidateam/plumpyA python workflows library that supports writing Processes with a well defined set of inputs and outputs that can be strung together.
Python★ 9↓ 62.5K/moAug 28, 2026

batman1m2001-cyber/OperonxWorkflow engine where ops can yield — same async DAG handles batch jobs and event-driven streaming pipelines (pipecat-style callbot, STT → LLM → TTS). Python frontend, drop-in Rust runtime; 2–3× faster on chains, 10–30× on production workloads. LLMs, agents, RAG, native compute as first-class ops.
Python★ 0↓ 3,514/moOct 9, 2026
PyPI · crates.io75Goodhealth index
Rust★ 15.5K↓ 21.8M/moSep 16, 2026

bryzgaloff/airflow-clickhouse-pluginThe most popular ClickHouse plugin for Airflow. 🔝 Top-1% downloads on PyPI: https://pypi.org/project/airflow-clickhouse-plugin! Based on mymarilyn/clickhouse-driver.
Python★ 187↓ 337.7K/moSep 12, 2026
PyPI · crates.io75Goodhealth index

bzsanti/oxidize-pythonPython bindings for oxidize-pdf — generate, parse, split, merge & manipulate PDFs with native Rust performance. No C deps, no Java, no subprocesses.
Python · Rust★ 6↓ 2,989/moOct 10, 2026
PyPI · crates.io · npm75Goodhealth index

colliery-io/graphqlite A SQLite extension that adds graph database capabilities with Cypher query language support and built-in graph algorithms.
C · Python★ 512↓ 2,790/moOct 17, 2026
Python★ 12↓ 1,551/moOct 22, 2026