PyPI · npm100Exceptionalhealth index
deepset-ai/haystackOpen-source AI orchestration framework for building context-engineered, production-ready LLM applications. Design modular pipelines and agent workflows with explicit control over retrieval, routing, memory, and generation. Built for scalable agents, RAG, multimodal applications, semantic search, and conversational systems.
Python★ 26.5KSep 16, 2026
PyPI99Exceptionalhealth index
ag2ai/ag2AG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3x
Python · MDX★ 4,891↓ 494.4K/moAug 28, 2026
PyPI99Exceptionalhealth index
microsoft/agent-frameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.
Python · C#★ 13.2K↓ 1.5M/moAug 27, 2026
PyPI99Exceptionalhealth index
pydantic/pydantic-aiHow Python does AI. Agents, realtime voice, image generation, embeddings. Every model, every interface, typed end to end.
Python★ 20K↓ 180M/moSep 16, 2026
PyPI · npm97Exceptionalhealth index
strands-agents/harness-sdkBuild an agent harness and control it end-to-end. Open-source SDK for production AI agents in Python & TypeScript - any model, any cloud.
Python · TypeScript · MDX★ 7,036↓ 39M/moAug 28, 2026
npm · Go · crates.io96Exceptionalhealth index
microsoft/agent-governance-toolkitAI Agent Governance Toolkit — Policy enforcement, zero-trust identity, execution sandboxing, and reliability engineering for autonomous AI agents. Covers 10/10 OWASP Agentic Top 10.
Python★ 6,138↓ 14.7K/moAug 28, 2026
PyPI94Exceptionalhealth index
evalstate/fast-agentCode, Build and Evaluate agents - excellent Model and Skills/MCP/ACP/A2A Support
Python★ 3,943Oct 20, 2026
npm · Maven94Exceptionalhealth index
iflytek/skillhubSelf-hosted, open-source agent skill registry for enterprises. Publish & version skill packages, govern with RBAC and audit logs, deploy on-premise with Docker or Kubernetes.
Java · TypeScript★ 4,901↓ 3,673/moAug 28, 2026
PyPI · npm94Exceptionalhealth index
omnigent-ai/omnigentOmnigent is an open-source AI agent framework and meta-harness: orchestrate Claude Code, Codex, Cursor, Pi, and custom agents — swap harnesses without rewriting, enforce policies and sandboxing, and collaborate in real time from any device.
Python · TypeScript★ 10KSep 16, 2026
PyPI94Exceptionalhealth index
vstorm-co/pydantic-deepagentsOpen-source, self-hosted Claude Code - a terminal AI assistant and the Python framework behind it. Tool-calling, sandboxed execution, multi-agent teams, skills, checkpoints, unlimited context - on Pydantic AI, any model.
Python★ 1,062↓ 141.9K/moSep 15, 2026
PyPI · npm93Exceptionalhealth index
Python · TypeScript★ 12↓ 3,775/moSep 8, 2026
npm · PyPI93Exceptionalhealth index
eigent-ai/eigentEigent: The Open Source Cowork Desktop - Local and Free Alternative to Claude Cowork and Codex
TypeScript · Python★ 15.6KOct 19, 2026
Go93Exceptionalhealth index
trpc-group/trpc-agent-goA Go framework for building production agent systems with graph workflows, tools, memory, A2A, AG-UI, MCP, evaluation, and observability.
Go★ 1,781Sep 11, 2026
Maven · PyPI92Excellenthealth index
Java★ 5,325Aug 28, 2026
PyPI92Excellenthealth index
Python★ 130Oct 19, 2026
PyPI91Excellenthealth index
Azure/GPT-RAGEnterprise-grade accelerator for agentic RAG on Azure. Built on Microsoft Foundry with Foundry IQ as the default retrieval backend, Microsoft Agent Framework orchestration, Zero-Trust architecture and IaC.
Python · PowerShell★ 1,176Sep 13, 2026
PyPI91Excellenthealth index
DougTrajano/pydantic-ai-skillsThis package implements Agent Skills (https://agentskills.io) support with progressive disclosure for Pydantic AI. Supports filesystem and programmatic skills.
Python★ 361↓ 3.3M/moAug 27, 2026
npm91Excellenthealth index
TypeScript · JavaScript★ 311↓ 38K/moOct 15, 2026
RubyGems91Excellenthealth index
Ruby★ 4,474Oct 20, 2026
PyPI · npm90Excellenthealth index
HKUDS/nanobotUltra-lightweight, open-source, self-hosted personal AI agent framework in Python with WebUI, tools, memory, MCP, multi-agent workflows, automation, and chat apps
Python · TypeScript★ 48.3KSep 18, 2026
npm90Excellenthealth index
inkeep/agentsCreate AI Agents in a No-Code Visual Builder or TypeScript SDK with full 2-way sync. For shipping AI assistants and multi-agent AI workflows.
TypeScript★ 1,425↓ 70.9K/moSep 12, 2026
npm · PyPI89Excellenthealth index
Azure/agent-app-orchestratorAgent orchestration service for the Agent Landing Zone, built on Microsoft Foundry Agent Service and Microsoft Agent Framework. Coordinates specialized agents for conversational experiences with grounded knowledge, NL2SQL and MCP tools.
Python★ 106Oct 22, 2026
PyPI89Excellenthealth index
UiPath/uipath-integrations-pythonA collection of Python SDKs that enable developers to build and deploy agents to the UiPath Cloud Platform using different agent frameworks
Python★ 10↓ 4,486/moOct 20, 2026
PyPI · Go · npm89Excellenthealth index
cordum-io/cordumThe action firewall for AI agents. Enforce policy and human approval before risky tool calls, shell commands, workflows, and production changes, with auditable evidence.
Go · TypeScript · Python★ 505↓ 14/moSep 17, 2026
npm · Go89Excellenthealth index
esengine/DeepSeek-ReasonixDeepSeek-native AI coding agent for your terminal. Engineered around prefix-cache stability — leave it running.
Go · TypeScript★ 35.6K↓ 28.4K/moSep 16, 2026
npm88Excellenthealth index
AgentsKit-io/agentskitThe complete toolkit for building AI agents in JavaScript. Lightweight core, React & Terminal UIs, autonomous runtime, tools, skills, memory, RAG and observability. Plug-and-play from chat UI to full agents.
TypeScript · MDX · JavaScript★ 36↓ 8,881/moOct 21, 2026
npm88Excellenthealth index
aeonfun/aeonThe most autonomous AI agent framework: runs unattended on GitHub Actions, self-healing skills, drives Claude Code, Grok, Codex & more. No approval loops. Configure once, forget forever.
JavaScript · Shell · TypeScript★ 778Oct 19, 2026
Hex88Excellenthealth index
agentjido/jido🤖 Autonomous agent framework for Elixir. Built for distributed, autonomous behavior and dynamic workflows.
Elixir★ 1,837↓ 24.4K/moSep 9, 2026
PyPI · npm88Excellenthealth index
bubbuild/bubBub it. Build it. A tiny agent runtime, composable with plugins.
Python · MDX★ 1,684↓ 23.1K/moOct 11, 2026
PyPI86Excellenthealth index
10xHub/AgentflowProduction-grade framework for building multi-agent AI systems. Graph-based orchestration, LLM-agnostic (OpenAI, Google GenAI, Anthropic), 3-layer memory (Redis cache + Postgres + vector store), live agents, parallel tool execution, and native MCP. Ships a full ecosystem: backend, REST API + CLI, TypeScript SDK, and React playground
Python★ 21↓ 717/moSep 19, 2026