
GMOD/ucsc-hub-jsread and write UCSC track and assembly hub files in node or the browser
TypeScript★ 5↓ 19.5K/moSep 15, 2026
PyPI · npm67Goodhealth index

haqaliz/contigAn agentic bioinformatics analyst: it runs the analysis on your own compute, self-heals failures, verifies the output, and returns a reproducible result.
Python · TypeScript★ 2↓ 1,094/moOct 21, 2026
crates.io · PyPI67Goodhealth index
C++ · Rust · Cython★ 45↓ 2,714/moOct 6, 2026
RubyGems67Goodhealth index
Ruby · C★ 12Sep 15, 2026

kcleal/dysguToolkit for calling structural variants using short or long reads
Cython · Python · C++★ 117↓ 1,920/moSep 13, 2026
crates.io63Moderatehealth index
Rust · Shell★ 38↓ 22/moOct 20, 2026
PyPI63Moderatehealth index

igvteam/igv-reportsPython application to generate self-contained pages embedding IGV visualizations, with no dependency on original input files.
Python · HTML★ 436↓ 3,026/moSep 13, 2026
crates.io63Moderatehealth index
Rust★ 152Oct 18, 2026
npm63Moderatehealth index
JavaScript★ 11↓ 231/moOct 18, 2026
crates.io62Moderatehealth index
Rust★ 107↓ 1,251/moSep 12, 2026
crates.io62Moderatehealth index
Rust★ 9↓ 8,536/moSep 18, 2026
PyPI62Moderatehealth index
Python★ 0↓ 3,939/moSep 26, 2026
npm60Moderatehealth index

GMOD/hicRead .hic contact matrix files in node or the browser
TypeScript★ 0↓ 5,002/moSep 21, 2026

brentp/somalierfast sample-swap and relatedness checks on BAMs/CRAMs/VCFs/GVCFs... "like damn that is one smart wine guy"
Nim · HTML★ 334Sep 12, 2026
RubyGems60Moderatehealth index
C · Ruby★ 14Oct 19, 2026
crates.io60Moderatehealth index
Rust · C++★ 165↓ 5/moSep 19, 2026
PyPI60Moderatehealth index
Python · C++★ 2↓ 2,400/moAug 25, 2026
PyPI59Moderatehealth index

JLSteenwyk/orthosnapa tree splitting and pruning algorithm for retrieving single-copy orthologs from gene family trees
Python★ 32↓ 221/moSep 10, 2026
npm57Moderatehealth index

biowasm/aioliFramework for building fast genomics web tools with WebAssembly and WebWorkers
JavaScript★ 121↓ 7,768/moSep 13, 2026
npm56Moderatehealth index

GMOD/gff-jsparse and format streams of GFF3, for node or webpack
TypeScript★ 10↓ 76.2K/moSep 15, 2026
Python · Shell · R★ 227Oct 19, 2026
PyPI56Moderatehealth index
Python★ 3↓ 503/moSep 8, 2026
PyPI53Moderatehealth index
Python★ 0↓ 2,492/moOct 6, 2026
PyPI51Moderatehealth index
Pep8★ 0↓ 2,227/moOct 12, 2026
Python★ 1Sep 14, 2026
crates.io48Weakhealth index
Rust★ 0↓ 2,636/moOct 3, 2026
CSS★ 5↓ 5,690/moSep 9, 2026
Python · Cython★ 19↓ 2,252/moSep 15, 2026
HTML · TypeScript★ 4↓ 169/moOct 18, 2026

liguowang/CrossMapCrossMap is a python program to lift over genome coordinates from one genome version to another.
Python★ 100↓ 7,250/moSep 20, 2026