PyPI98Exceptionalhealth index
Python · C★ 14.9KAug 4, 2026
PyPI98Exceptionalhealth index

spack/spackA flexible package manager that supports multiple versions, configurations, platforms, and compilers.
Python★ 5,109Aug 22, 2026
PyPI97Exceptionalhealth index

InsightSoftwareConsortium/ITKInsight Toolkit (ITK) -- Official Repository. ITK builds on a proven, spatially-oriented architecture for processing, segmentation, and registration of scientific images in two, three, or more dimensions.
C++★ 1,641Aug 13, 2026
—94Exceptionalhealth index
CliMA/ClimaAtmos.jlGPU-capable global atmosphere model of the CliMA Earth System Model, designed for calibration with data assimilation and machine learning
Julia★ 121Jul 19, 2026
crates.io94Exceptionalhealth index

tracel-ai/burnBurn is a next generation tensor library and Deep Learning Framework that doesn't compromise on flexibility, efficiency and portability.
Rust★ 15.7K↓ 686.9K/moAug 5, 2026
PyPI93Exceptionalhealth index
glotzerlab/freudPowerful, efficient particle trajectory analysis in scientific Python.
C++ · Python★ 324↓ 8,442/moJul 22, 2026
Go93Exceptionalhealth index

goplus/xgoXGo is a programming language that reads like plain English. But it's also incredibly powerful — it lets you leverage assets from C/C++, Go, Python, and JavaScript/TypeScript, creating a unified software engineering ecosystem. Our vision is to enable everyone to become a builder of the world.
Go★ 9,452Aug 29, 2026
PyPI92Excellenthealth index
Python · C★ 281Jul 26, 2026
PyPI90Excellenthealth index
Python · Cython · C★ 919↓ 823K/moJul 21, 2026
PyPI90Excellenthealth index
Python★ 142↓ 2,580/moJul 20, 2026

CliMA/ClimaLand.jlModular, GPU-capable land surface model of the CliMA Earth System Model, designed for data-driven parameterizations
Julia★ 73Aug 17, 2026
crates.io89Excellenthealth index

smartcorelib/smartcoreA comprehensive library for machine learning and numerical computing. Apply Machine Learning with Rust leveraging first principles.
Rust★ 949↓ 50.4K/moAug 23, 2026
EnzymeAD/EnzymeHigh-performance automatic differentiation of LLVM and MLIR.
LLVM · C++★ 1,648Jul 18, 2026
PyPI88Excellenthealth index

chaobrain/saiunitUnit-aware computations for AI-driven scientific computing, compatible with NumPy, JAX, PyTorch, CuPy, Dask, ndonnx.
Python★ 20Aug 17, 2026
NuGet87Excellenthealth index

SciSharp/NumSharpHigh Performance Computation for N-D Tensors in .NET, similar API to NumPy.
C#★ 1,478Sep 6, 2026
crates.io87Excellenthealth index
Rust · HTML★ 132↓ 17.6K/moSep 5, 2026
PyPI86Excellenthealth index

K-Dense-AI/scientific-agent-skillsTurn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 170,000+ scientists worldwide. 158 ready-to-use skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.
Python★ 32.6KAug 5, 2026
npm · PyPI84Excellenthealth index
TypeScript · Zig★ 375↓ 2,386/moJul 21, 2026

casadi/casadiCasADi is a symbolic framework for numeric optimization implementing automatic differentiation in forward and reverse modes on sparse matrix-valued computational graphs. It supports self-contained C-code generation and interfaces state-of-the-art codes such as SUNDIALS, IPOPT etc. It can be used from C++, Python or Matlab/Octave.
C++ · SWIG · C★ 2,272Aug 13, 2026
PyPI83Excellenthealth index
Python★ 2↓ 2,503/moJul 22, 2026
Go80Excellenthealth index
Go★ 142Aug 20, 2026
crates.io78Goodhealth index

Axect/PeroxideRust numeric library with high performance and friendly syntax
Rust★ 724↓ 113.1K/moAug 22, 2026
crates.io78Goodhealth index
Rust★ 8↓ 3,448/moAug 22, 2026
crates.io78Goodhealth index
cpmech/russellRust Scientific Library. ODE, DAE, and PDE solvers. Special functions (Bessel, Elliptic, Beta, Gamma, Erf). Linear algebra. Sparse solvers. Probability distributions. Tensor calculus. Numerical continuation.
Rust★ 191↓ 2,398/moJul 28, 2026
elkins/synth-pdbGenerate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1↓ 3,758/moJul 15, 2026
PyPI · npm78Goodhealth index
Python★ 25↓ 3,845/moJul 16, 2026
crates.io77Goodhealth index

rust-ndarray/ndarrayndarray: an N-dimensional array with array views, multidimensional slicing, and efficient operations
Rust★ 4,311↓ 8.2M/moAug 11, 2026
Python★ 2,069↓ 1.5M/moAug 13, 2026
Julia★ 154Jul 26, 2026
elkins-lab/synth-pdbGenerate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1Jul 17, 2026