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#bioinformatics

Every repository in the public record carrying this tag — from its GitHub topics or the keywords its package registries publish. Health is measured under the same versioned methodology as the rest of the record.

98 records
Tagged “bioinformatics”Ranked by health index
PyPI
88Excellenthealth index
scverse/anndata
Annotated data.
Python★ 759↓ 1.7M/moJul 21, 2026
BSD-3-ClauseJul 21, 2026 · metrics 1.13.0
PyPI
87Excellenthealth index
scverse/scanpy
Single-cell analysis in Python. Scales to >100M cells.
Python★ 2,522↓ 1M/moJul 21, 2026
BSD-3-ClauseJul 21, 2026 · metrics 1.13.0
PyPI · npm
80Goodhealth index
plotly/dash
Data Apps & Dashboards for Python. No JavaScript Required.
Python · TypeScript · HTML★ 24.3KJul 18, 2026
MITJul 18, 2026 · metrics 1.13.0
PyPI
77Goodhealth index
biopython/biopython
Official git repository for Biopython (originally converted from CVS)
Python★ 5,131Jul 22, 2026
Custom licenseJul 22, 2026 · metrics 1.13.0
PyPI
76Goodhealth index
scverse/rapids-singlecell
rapids-singlecell: GPU-accelerated framework for scRNA analysis
Python · Cuda★ 386Jul 20, 2026
MITJul 20, 2026 · metrics 1.13.0
74Goodhealth index
samtools/htslib
C library for high-throughput sequencing data formats
C★ 936↓ 0/moJul 13, 2026
Custom licenseJul 13, 2026 · metrics 1.13.0
PyPI
73Goodhealth index
ablab/IsoQuant
Transcript discovery and quantification with long RNA reads (Nanopores and PacBio)
Python★ 233Jul 17, 2026
Custom licenseJul 17, 2026 · metrics 1.13.0
PyPI
73Goodhealth index
pysam-developers/pysam
Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.
Cython · Python★ 900↓ 1.2M/moJul 21, 2026
MITJul 21, 2026 · metrics 1.13.0
PyPI · crates.io
71Goodhealth index
biotite-dev/biotite
A comprehensive library for computational molecular biology
Python · Rust★ 966↓ 5.2M/moJul 18, 2026
BSD-3-ClauseJul 18, 2026 · metrics 1.13.0
PyPI · crates.io
71Goodhealth index
genomoncology/biomcp
BioMCP: Biomedical Model Context Protocol
Rust · Python★ 554Jul 21, 2026
MITJul 21, 2026 · metrics 1.13.0
PyPI
70Goodhealth index
helicalAI/helical
A framework for state-of-the-art pre-trained bio foundation models on genomics and transcriptomics modalities.
Python★ 221↓ 0/moJul 13, 2026
AGPL-3.0Jul 13, 2026 · metrics 1.13.0
PyPI
68Moderatehealth index
EBI-Metagenomics/genome_uploader
Python script to upload bins and MAGs to ENA (European Nucleotide Archive)
Python★ 24Jul 17, 2026
Apache-2.0Jul 17, 2026 · metrics 1.13.0
PyPI
68Moderatehealth index
EBi-Metagenomics/mgnify-pipelines-toolkit
This Python package contains a collection of scripts and tools for including in MGnify pipelines
Python★ 1↓ 1,147/moJul 17, 2026
Apache-2.0Jul 17, 2026 · metrics 1.13.0
crates.io · npm
67Moderatehealth index
COMBINE-lab/salmon
🐟 🍣 🍱 Highly-accurate & wicked fast transcript-level quantification from RNA-seq reads using selective alignment
Rust★ 918Jul 16, 2026
BSD-3-ClauseJul 16, 2026 · metrics 1.13.0
Maven · npm · PyPI +1
67Moderatehealth index
PharmGKB/PharmCAT
The Pharmacogenomic Clinical Annotation Tool
Java · Python★ 183Jul 20, 2026
MPL-2.0Jul 20, 2026 · metrics 1.13.0
PyPI
67Moderatehealth index
elkins/synth-pdb
Generate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1↓ 3,758/moJul 15, 2026
MITJul 15, 2026 · metrics 1.13.0
npm
67Moderatehealth index
iGVteam/igv.js
Embeddable genomic visualization component based on the Integrative Genomics Viewer
JavaScript · HTML★ 728↓ 81.9K/moJul 17, 2026
MITJul 17, 2026 · metrics 1.13.0
PyPI
67Moderatehealth index
michael-denyer/jamma
JAMMA (Highly-Accelerated Multi-method Mixed-model Association) -- a fast and modern Python and C reimplementation of GEMMA for large-scale GWAS.
Python · C★ 1Jul 20, 2026
GPL-3.0Jul 20, 2026 · metrics 1.13.0
PyPI
67Moderatehealth index
pdbeurope/pdbe-mcp-servers
PDBe MCP Servers integrate Protein Data Bank Europe resources with LLMs via Model Context Protocol. Provides seamless access to protein structure data through API tools and graph database schema assistance for intelligent Cypher query generation, bridging structural biology and AI research.
Python★ 36↓ 3,297/moJul 17, 2026
Apache-2.0Jul 17, 2026 · metrics 1.13.0
PyPI
67Moderatehealth index
rhysnewell/aviary
A hybrid assembly and MAG recovery pipeline (and more!)
Python · HTML★ 109↓ 205/moJul 17, 2026
GPL-3.0Jul 17, 2026 · metrics 1.13.0
npm
66Moderatehealth index
cyanheads/clinicaltrialsgov-mcp-server
Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP.
TypeScript★ 81↓ 9,182/moJul 13, 2026
Apache-2.0Jul 13, 2026 · metrics 1.13.0
PyPI
66Moderatehealth index
sokrypton/ColAbFold
Making Protein folding accessible to all!
Jupyter Notebook★ 2,836↓ 12.3K/moJul 17, 2026
MITJul 17, 2026 · metrics 1.13.0
PyPI
65Moderatehealth index
JLSteenwyk/PhyKIT
a UNIX shell toolkit for processing and analyzing multiple sequence alignments and phylogenies
Python★ 88Jul 21, 2026
MITJul 21, 2026 · metrics 1.13.0
PyPI
63Moderatehealth index
brentp/cyvcf2
cython + htslib == fast VCF and BCF processing
Cython · Python★ 446Jul 21, 2026
MITJul 21, 2026 · metrics 1.13.0
PyPI
63Moderatehealth index
elkins-lab/synth-pdb
Generate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1Jul 17, 2026
MITJul 17, 2026 · metrics 1.13.0
PyPI
62Moderatehealth index
ensembl/ensembl-py
Python Ensembl code source repository
Python★ 6Jul 17, 2026
Apache-2.0Jul 17, 2026 · metrics 1.13.0
PyPI
61Moderatehealth index
CDCgov/tostadas
🧬 💻 TOSTADAS → Toolkit for Open Sequence Triage, Annotation and DAtabase Submission
Python · Nextflow · Batchfile★ 29Jul 18, 2026
Apache-2.0Jul 18, 2026 · metrics 1.13.0
PyPI
61Moderatehealth index
PDBeurope/ccdutils
A set of python tools to deal with PDB chemical components definitions for small molecules, taken from the wwPDB Chemical Component Dictionary, uses RDKit
Python★ 82Jul 15, 2026
Apache-2.0Jul 15, 2026 · metrics 1.13.0
PyPI
61Moderatehealth index
biocore/SORTMeRNA
SortMeRNA: next-generation sequence filtering and alignment tool
C++ · C · Jinja★ 297Jul 16, 2026
GPL-3.0Jul 16, 2026 · metrics 1.13.0
PyPI
60Moderatehealth index
Electrostatics/mmcif_pdbx
Yet another version of PDBx/mmCIF Python implementation
Python★ 9Jul 15, 2026
CC0-1.0Jul 15, 2026 · metrics 1.13.0