PyPI88Excellenthealth index
scverse/anndataAnnotated data.
Python★ 759↓ 1.7M/moJul 21, 2026
PyPI87Excellenthealth index
scverse/scanpySingle-cell analysis in Python. Scales to >100M cells.
Python★ 2,522↓ 1M/moJul 21, 2026
PyPI · npm80Goodhealth index
plotly/dashData Apps & Dashboards for Python. No JavaScript Required.
Python · TypeScript · HTML★ 24.3KJul 18, 2026
biopython/biopythonOfficial git repository for Biopython (originally converted from CVS)
Python★ 5,131Jul 22, 2026
scverse/rapids-singlecellrapids-singlecell: GPU-accelerated framework for scRNA analysis
Python · Cuda★ 386Jul 20, 2026
samtools/htslibC library for high-throughput sequencing data formats
C★ 936↓ 0/moJul 13, 2026
ablab/IsoQuantTranscript discovery and quantification with long RNA reads (Nanopores and PacBio)
Python★ 233Jul 17, 2026
pysam-developers/pysamPysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.
Cython · Python★ 900↓ 1.2M/moJul 21, 2026
PyPI · crates.io71Goodhealth index
biotite-dev/biotiteA comprehensive library for computational molecular biology
Python · Rust★ 966↓ 5.2M/moJul 18, 2026
PyPI · crates.io71Goodhealth index
genomoncology/biomcpBioMCP: Biomedical Model Context Protocol
Rust · Python★ 554Jul 21, 2026
helicalAI/helicalA framework for state-of-the-art pre-trained bio foundation models on genomics and transcriptomics modalities.
Python★ 221↓ 0/moJul 13, 2026
PyPI68Moderatehealth index
EBI-Metagenomics/genome_uploaderPython script to upload bins and MAGs to ENA (European Nucleotide Archive)
Python★ 24Jul 17, 2026
PyPI68Moderatehealth index
EBi-Metagenomics/mgnify-pipelines-toolkitThis Python package contains a collection of scripts and tools for including in MGnify pipelines
Python★ 1↓ 1,147/moJul 17, 2026
crates.io · npm67Moderatehealth index
COMBINE-lab/salmon🐟 🍣 🍱 Highly-accurate & wicked fast transcript-level quantification from RNA-seq reads using selective alignment
Rust★ 918Jul 16, 2026
Maven · npm · PyPI +167Moderatehealth index
PharmGKB/PharmCATThe Pharmacogenomic Clinical Annotation Tool
Java · Python★ 183Jul 20, 2026
PyPI67Moderatehealth index
elkins/synth-pdbGenerate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1↓ 3,758/moJul 15, 2026
npm67Moderatehealth index
iGVteam/igv.jsEmbeddable genomic visualization component based on the Integrative Genomics Viewer
JavaScript · HTML★ 728↓ 81.9K/moJul 17, 2026
PyPI67Moderatehealth index
michael-denyer/jammaJAMMA (Highly-Accelerated Multi-method Mixed-model Association) -- a fast and modern Python and C reimplementation of GEMMA for large-scale GWAS.
Python · C★ 1Jul 20, 2026
PyPI67Moderatehealth index
pdbeurope/pdbe-mcp-serversPDBe MCP Servers integrate Protein Data Bank Europe resources with LLMs via Model Context Protocol. Provides seamless access to protein structure data through API tools and graph database schema assistance for intelligent Cypher query generation, bridging structural biology and AI research.
Python★ 36↓ 3,297/moJul 17, 2026
PyPI67Moderatehealth index
rhysnewell/aviaryA hybrid assembly and MAG recovery pipeline (and more!)
Python · HTML★ 109↓ 205/moJul 17, 2026
npm66Moderatehealth index
cyanheads/clinicaltrialsgov-mcp-serverSearch ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP.
TypeScript★ 81↓ 9,182/moJul 13, 2026
PyPI66Moderatehealth index
sokrypton/ColAbFoldMaking Protein folding accessible to all!
Jupyter Notebook★ 2,836↓ 12.3K/moJul 17, 2026
PyPI65Moderatehealth index
JLSteenwyk/PhyKITa UNIX shell toolkit for processing and analyzing multiple sequence alignments and phylogenies
Python★ 88Jul 21, 2026
PyPI63Moderatehealth index
brentp/cyvcf2cython + htslib == fast VCF and BCF processing
Cython · Python★ 446Jul 21, 2026
PyPI63Moderatehealth index
elkins-lab/synth-pdbGenerate realistic PDB files with mixed secondary structures for testing, education and bioinformatics tool development. Jupyter Notebook tutorials are available to visualize the concepts..
Python★ 1Jul 17, 2026
PyPI62Moderatehealth index
ensembl/ensembl-pyPython Ensembl code source repository
Python★ 6Jul 17, 2026
PyPI61Moderatehealth index
CDCgov/tostadas🧬 💻 TOSTADAS → Toolkit for Open Sequence Triage, Annotation and DAtabase Submission
Python · Nextflow · Batchfile★ 29Jul 18, 2026
PyPI61Moderatehealth index
PDBeurope/ccdutilsA set of python tools to deal with PDB chemical components definitions for small molecules, taken from the wwPDB Chemical Component Dictionary, uses RDKit
Python★ 82Jul 15, 2026
PyPI61Moderatehealth index
biocore/SORTMeRNASortMeRNA: next-generation sequence filtering and alignment tool
C++ · C · Jinja★ 297Jul 16, 2026
PyPI60Moderatehealth index
Electrostatics/mmcif_pdbxYet another version of PDBx/mmCIF Python implementation
Python★ 9Jul 15, 2026